High-Potency Vitamin D3
for Immunity, Bones & Vitality
1 capsule weekly for strong bones, clear mood & resilient immunity
Vitamin D3
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Overview: Product Description
Meet Mega D3 (Cholecalciferol) 40 000 IU, a premium high-potency vitamin D3 supplement from Doc Frank designed to support optimal health in modern lifestyles. Each capsule delivers 40 000 IU of vitamin D3 – making it simple to maintain healthy levels even with limited sun exposure. This formula aids immune resilience, bone and muscle health, mood regulation and everyday vitality. With just one weekly dose many users find this an easy, effective way to bolster a key nutrient that’s often deficient.
Why Mega D3?
"Vitamin D3 - the sunshine vitamin"
Benefits
- Strong bone and muscle support via vitamin D3 enhancing calcium absorption and skeletal strength.
- Enhanced immune resilience: vitamin D3 modulates innate and adaptive immune functions, supports mucosal defence and may reduce risk of certain immune-related conditions.
- Mood and vitality support: maintaining optimum vitamin D levels correlates with better mood balance, energy and general well-being (as highlighted on the Integrow site).
- Easy dosing: one high-strength capsule per week cuts down on daily pill burden and simplifies supplementation.
More Advantages
- Exceptional value: delivering 40 000 IU per capsule means fewer doses required per month.
- High bioavailability: provides the superior form of vitamin D (D3 / cholecalciferol) which research shows is more effective than vitamin D2.
- Well-absorbed in capsule format for convenience and ease of use.
- Designed by a trusted brand focused on evidence-based supplementation and holistic health.
- Suitable as a foundational nutrient support product that can be combined with other targeted nutrients for specific health goals.
Supplement Profile
Active Ingredients
- Cholecalciferol (Vitamin D3) – 40 000 IU (per capsule)
- Supports calcium and phosphorus metabolism, promoting bone mineralisation and strength.
- Enhances immune system regulation by modulating gene expression in immune cells, reducing inflammatory signalling and supporting innate defences.
- Improves mood and cognitive function indirectly via better neuronal signalling and muscle function.
Supplement Facts
- Serving size: 1 capsule
- Servings per container: 30 (i.e., 1 capsule weekly covers ~30 weeks)
- Format: softgel/capsule
- Packaging: Bottle containing 30 capsules.
- Active component: Cholecalciferol (Vitamin D3) 40 000 IU per capsule.
Inactive Ingredients
- Capsule shell and excipients typical of vitamin capsule formulations
Allergens
- Present: None reported
- Not Present: Gluten, dairy, soy, nuts, shellfish
Dietary Compliance
- Vegan friendly: No
- Keto friendly: Yes
- Dairy free: Yes
- Fish/pork free: Yes
Precautions
- Pregnancy & breastfeeding: Consult your healthcare professional before use.
- Age restrictions: Intended for adults; children should only use under professional guidance.
- Contraindications / interactions: Individuals with hypercalcaemia, sarcoidosis, kidney stones or on high-dose calcium should seek medical advice; vitamin D3 may interact with certain medications (e.g., thiazides, corticosteroids).
- Side effects: At typical dosing safe; rarely high-dose vitamin D3 can cause elevated calcium, kidney issues. The risk at recommended use is minimal but monitor under clinical guidance.
- Medical conditions: If you have chronic kidney disease, chronic granulomatous disease, or other disorders of calcium/vitamin D metabolism, use only under supervision.
Storage Instructions
- Store in a cool, dry place away from direct sunlight.
- Keep the bottle tightly closed and out of reach of children.
- Avoid excessive heat or humidity.
Directions
- Adults: Take 1 capsule weekly, or as directed by your healthcare professional.
- Take with food containing fat (vitamin D is fat-soluble) for optimal absorption.
- Your body synthesises vitamin D3 (cholecalciferol) in skin via sunlight, then converts it in liver and kidneys to its active form, which binds to vitamin D receptors (VDR) in many tissues.
- In Mega D3, the high-dose cholecalciferol elevates serum 25-hydroxyvitamin D levels toward or within optimal ranges (e.g., >30 ng/mL or ~75 nmol/L) which have been associated with improved calcium absorption, reduced PTH, improved immune regulation.
- For bone and muscle: By improving calcium and phosphorus absorption, vitamin D supports mineralisation of bone matrix and muscle function, reducing risk of weakness.
- For immunity: Vitamin D3 modulates immune function—down-regulating pro-inflammatory cytokines, enhancing expression of antimicrobial peptides (cathelicidin, defensins), and supporting immune tolerance.
- The weekly dosing strategy means the body has consistent high serum exposure and sustained biological effect with fewer doses, reducing pill fatigue and improving compliance.
- Adults with limited sun exposure (indoor jobs, overcast climates, sun-block usage) seeking to maintain healthy vitamin D levels.
- Individuals with known low vitamin D levels (via blood test) wanting a potent corrective or maintenance option.
- Older adults needing bone-health support (bones, joints, muscle strength) or immune resilience.
- People experiencing mood fluctuations, fatigue or muscle weakness associated with sub-optimal vitamin D status.
- Athletes, fitness-enthusiasts or anyone with higher nutrient demands who benefit from enhanced muscle and immune support.
- Those using other Integrow holistic-health supplements and looking for a foundational nutrient to pair with.
- High-potency deliverables: 40 000 IU per capsule allows once-weekly dosing for convenience and potency — fewer capsules, easier routine.
- Superior form: Uses cholecalciferol (vitamin D3) — research shows D3 is more effective than D2.
- Trusted brand heritage: From Integrow Health, a company committed to holistic & evidence-informed nutrition.
- Simplified regimen: Minimises dosing frequency (once weekly) reducing complexity.
- Designed for modern lifestyles: Recognises sun-exposure limitations and offers corrective or maintenance dosing.
- Affordability and value: Delivered in a 30-capsule bottle, excellent cost-to-benefit ratio for high-dose formula.
- Quality assurance: Includes customer-reviewed product, 4.9★ average rating from verified buyers.
- Synergy-ready: Works well alongside other Integrow products (e.g., magnesium, vitamin K2) to support bone-immune-muscle triad.
- Evidence-aligned: Backed by science emphasising vitamin D3 status for immunity, bone health and general vitality.
Science
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A meta-analysis found vitamin D3 supplementation had a protective effect on bone mineral density at lumbar spine and femoral neck sites. PubMed
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An immunologic review found low vitamin D levels associated with increased risk of autoimmune diseases, infections, and impaired immune regulation; vitamin D3 supplementation supports immune cell gene expression related to innate and adaptive immunity. PubMed
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Research shows vitamin D3 (versus D2) has superior effects on interferon signalling, an important immune defence pathway. Medscape
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While large trials show limited benefit in vitamin D-replete populations, consensus remains that correction of deficiency is vital and scientifically supported. Nature
Reviews
Levels improving
My husband and I have just started using our Vit.D3 supplement. The order was hassle free and quick and we hope our Vit. D levels will improve iver the next few months. I think it is an excellent quality at a very good price.
No longer sick
We have been on the 5 products of Mega D3, Re-mind, Phaphama Vitality Tonic, Cancer Bush (Sutherlandia frutescens), Fulvic Acid 400mg and Bravo! 60 capsules. Since we have been on these supplements we haven’t been sick in over a year and 5 months.
High dose
Very happy especially with the high dose which is not easy to find elsewhere. I will be ordering again when I run out.
Good supply & quality
I had been reading about Cholecalciferol and was battling to try and find a good supplier so I am delighted I now have a good source of Vit D3 top up in easy to take capsule form. Taking one capsule twice a week so a bottle of 30 will last a good while.
Can't live without it
Neither myself nor my husband, nor several members of family and friends could live with out this product! We generally take 1 per week unless we’re feeling ‘under the weather’ then we take 2 per week.
